Intrahepatic portosystemic shunt (TIPS) procedure in patient groups To examine the generalizability of a model previously created toĮstimate survival of patients undergoing the transjugular Verifiable, and easily obtained variables. Necessitates a disease severity index based on generalizable, Priorities in allocating organs for liver transplantation and 2001Ī recent mandate emphasizes severity of liver disease to determine Kamath PS, Wiesner RH, Malinchoc M, Kremers W, Therneau TM, KosbergĬL, D'Amico G, Dickson ER, Kim WR.(logarithm of a number below one will be a negative number) This score is now used by the United Network for Organ Sharing (UNOS) and Eurotransplantįor prioritizing allocation of liver transplants instead of the olderĪny value less than one is given a value of 1 to prevent a negative value Patients will automatically revert to the previous MELD score. Must be updated according to the UNOS Recertification Schedule, otherwise Ranges in value from 6 (lowest priority) to 40 (highest priority). Patient’s serum creatinine, INR and bilirubin, as these were found to mostĪccurately correlate with mortality within a three month period. Liver transplant in the next three months. Probability of death from liver disease and how urgently an individual needs a The Model for End-Stage Liver Disease (MELD) is a useful tool in predicting the (or) received 24 hours of continuous veno-venous hemodialysis (CVVHD) Has the patient had dialysis at least twice in the prior 7 days MELD scores are reported as whole numbers, so the result of the equation above MELD Score = 10 x (0.957 x Ln(serum creatinine mg/dL) + 0.378 x Ln(serum bilirubin Conversely, multivariate analysis of these five factors in patients with MELD scores 20-29 found that age ( P = 0.012), etiology ( P = 0.024), serum sodium ( P = 0.005) and ascites ( P = 0.017) were independent predictors of 3-month mortality MELD score was not an independent predictor of mortality in patients with MELD score 20-29 once other factors were taken into account.MELD Score (Model For End-Stage Liver Disease) Of these five factors, only MELD score ( P = 0.015) was independent predictor of 3-month mortality in patients with MELD score ≥30. When the remaining predictors significant at P < 0.05 were subjected to binary logistic regression, only age ( P = 0.013), etiology ( P = 0.009), serum sodium ( P = 0.026), ascites ( P = 0.025), and MELD score ( P = 0.025) were independent predictors of 3-month mortality in all patients ( Table 6 ). In multivariate analyses to identify predictors of 3-month mortality ( Table 5 ), the significant factors (sex, age, etiology, serum sodium, ascites, MELD score) were entered in multivariate logistic regression model. Prognostic factors associated with 3-month mortality in multivariate analysis. Univariate analysis showed that the mortality of patients with MELD score ≥40 did not seem to be associated with sex ( P = 0.846), age ( P = 0.743), etiology ( P = 0.851), serum sodium ( P = 0.901) or ascites ( P = 0.517). In univariate analysis, we analyzed the prognostic value of clinical and biological variables in 3-month mortality of patients with MELD score ≥40 ( Table 4 ). Univariate prognostic analysis of the 3-month mortality of patients with MELD score ≥40. The mortality of patients with MELD score 30-39 did not seem to be associated with sex ( P = 0.897), serum sodium ( P = 0.236) or ascites ( P = 0.396). Univariate analysis showed that the following factors had significant prognostic value: age ( P = 0.046), and etiology ( P = 0.042). In univariate analysis, we analyzed the prognostic value of clinical and biological variables in 3-month mortality of patients with MELD score 30-39 ( Table 3 ). Univariate prognostic analysis of the 3-month mortality of patients with MELD score 30-39. The mortality of patients with MELD score 20-29 did not seem to be associated with sex ( P = 0.973).

Univariate analysis showed that the following factors had significant prognostic value: age ( P = 0.047), etiology ( P = 0.039), serum sodium ( P = 0.029) and ascites ( P = 0.031). In univariate analysis, we analyzed the prognostic value of clinical and biological variables in 3-month mortality of patients with MELD score 20-29 ( Table 2 ). Univariate prognostic analysis of the 3-month mortality of patients with MELD score 20-29. Factors Influencing the Prediction Ability of MELD Scoring System

Meld score 24 prognosis